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INDICATION AND IMPORTANT SAFETY INFORMATION

INDICATION Sofdra® (sofpironium) topical gel, 12.45% is a prescription anticholinergic medicine used on the skin to treat excessive underarm sweating (primary axillary hyperhidrosis) in adults and children 9 years of age and older. IMPORTANT SAFETY INFORMATION Sofdra is for use on the skin in the underarm area only. After applying Sofdra, wash your hands right away and do not touch your underarms. Sofdra is flammable. Avoid heat and flame while applying Sofdra. Who should not use Sofdra? Do not use Sofdra if you have certain medical conditions that can be made worse by taking an anticholinergic medicine, such as glaucoma, severe ulcerative colitis (UC) or other serious bowel problems, myasthenia gravis, and Sjogren’s syndrome. What should I tell my healthcare provider before using Sofdra? <ul> <li>Tell your healthcare provider about all of your medical conditions, including prostate, bladder or kidney problems, problems passing urine, if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if Sofdra will harm your unborn baby or pass into your breast milk.</li> <li>Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, especially any anticholinergic medicines.</li> </ul> What are possible side effects of Sofdra? Serious side effects may include: <ul> <li>Urinary retention. Stop using Sofdra and call your healthcare provider right away if you have difficulty urinating, urinate frequently or in a weak stream or drips, a full bladder or difficulty emptying your bladder.</li> <li>Problems with control of your body temperature. Stop using Sofdra and call your healthcare provider right away if you have decreased sweating that develops into symptoms of heat illness (e.g., hot, red skin; passing out; fast, weak pulse; fast, shallow breathing; increased body temperature).</li> <li>Blurred vision. Stop using Sofdra, call your healthcare provider right away, and do not drive or operate machinery or do hazardous work until your vision is clear. </li> </ul> The most common side effects of Sofdra include dry mouth; blurred vision; pain, redness, swelling, itching, and irritation in the underarm area; dilation of the pupils of your eyes; and problems with urination. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <a href="https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program" target="_blank">www.fda.gov/medwatch</a> or call 1-800-FDA-1088. You may also report side effects to Botanix at 1-866-763-6337. Keep Sofdra and all medicines out of the reach of children. Please see full <a href="https://www.sofdra.com/pdfs/prescribing-information.pdf" target="_blank">Prescribing Information</a>, <a href="https://www.sofdra.com/pdfs/patient-information.pdf" target="_blank">Patient Product Information</a>, and <a href="https://www.sofdra.com/pdfs/instructions-for-use.pdf" target="_blank">Instructions for Use</a>.

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Simply answer a few medical questions without obligation to learn if Sofdra may be right for you. Are you here for yourself or your child that is 9 years of age or older?

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IMPORTANT SAFETY INFORMATION AND INDICATION

Welcome to GetSofdra.com, the exclusive telehealth site for Sofdra. Begin by registering and answering a few medical questions to see if Sofdra may be right for you. Then connect with a telehealth provider.** If prescribed Sofdra, get fast, free delivery to your door.

Get Sofdra® for $0 pharmacy copay* Sweat less, pay less

Answer a few questions about yourself and your symptoms.

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1. Register and complete medical questionnaire

Connect with an independent telehealth provider at your convenience at the place of your choice.

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2. Schedule and pay for your telehealth visit

If Sofdra is right for you, request a prescription during your visit.

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3. Speak with a telehealth provider

Once your prescription is approved, Sofdra will be delivered directly to you.

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4. Receive your prescription

You can connect with an independent licensed healthcare provider from the comfort of your home.

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*With commercial insurance, such as employer-sponsored plans. $0 pharmacy copay offer not available to patients with federal or state government-funded insurance, such as Medicare, Medicaid, Tricare, and CHIP. Offer <a href="https://www.sofdra.com/pdfs/terms-and-conditions.pdf" target="_blank" style="text-decoration: underline;">terms and conditions</a> apply. **Single $35 telehealth visit fee To learn more about Sofdra, <a href="https://sofdra.com" target="_blank" style="font-weight: bold; text-decoration: underline;">click here</a>. <a href="https://sendrx.com/sofdra" target="_blank" style="font-weight: bold; text-decoration: underline;"> I already have a Sofdra prescription </a>

Learn how Sofdra can help treat your excessive sweating and request a prescription. If approved, we'll ship your prescription directly to your doore

UpScript gives you fast access to trusted prescription medication. Select your treatment, speak with a private online doctor and get it delivered right to your doorstep.

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Register, access your account details, schedule and pay for your online visit all in one place. For parents registering their child for a prescription, begin by entering your child's first and last name below. Ensure all information provided on the following pages is accurate and specific to your child. Already registered? Please click the "Already have an account?" link on this page to log in.

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Excessive underarm sweating (primary axillary hyperhidrosis) is a medical condition where underarm sweating occurs beyond what is needed to maintain normal body temperature. Talk to an independent, licensed telehealth provider today to see if Sofdra might be right for you.

Do you have excessive underarm sweating?

NOTE: By clicking the New Prescription button, you acknowledge that if you have government insurance that does not cover Sofdra, or if you are uninsured, your co-pay could be as much as $967.50

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Find out if Sofdra™ (sofpironium bromide) gel, 12.45% is the right treatment for your excessive underarm sweating (primary axillary hyperhidrosis)....